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The Ultimate Juicy & Easy Classic Meatloaf with the Perfect Tangy Glaze

Close-up of a juicy meatloaf topped with a thick, bright red glaze, with one slice cut and resting beside the main loaf.

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Make the best homemade beef meatloaf that is consistently juicy, tender, and flavorful. This easy recipe uses simple ingredients and features a classic sweet and tangy ketchup glaze for a comforting family dinner.

Ingredients

Scale
  • 2 lbs ground beef (80/20 recommended)
  • 1 cup Stove Top Stuffing mix (or plain breadcrumbs)
  • 1/2 cup milk
  • 1 large egg, lightly beaten
  • 1/2 cup finely chopped onion
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 1/4 teaspoon garlic powder
  • 1/4 cup ketchup (for the mix)
  • 1/2 cup ketchup (for the glaze)
  • 1/4 cup packed brown sugar (for the glaze)
  • 1 tablespoon apple cider vinegar (for the glaze)

Instructions

  1. Preheat your oven to 350°F (175°C). Lightly grease a loaf pan or line a baking sheet with parchment paper.
  2. In a large bowl, combine the ground beef, stuffing mix, milk, egg, chopped onion, salt, pepper, garlic powder, and 1/4 cup of ketchup. Mix gently with your hands until just combined. Do not overmix.
  3. Form the mixture into a loaf shape on your prepared pan or press it into the loaf pan.
  4. In a small bowl, whisk together the 1/2 cup ketchup, brown sugar, and apple cider vinegar to create the glaze.
  5. Spread half of the glaze evenly over the top of the meatloaf.
  6. Bake for 45 minutes.
  7. Remove the meatloaf from the oven and spread the remaining glaze over the top.
  8. Return to the oven and bake for another 15 to 20 minutes, or until the internal temperature reaches 160°F (71°C).
  9. Let the meatloaf rest for 10 minutes before slicing and serving.

Notes

  • For an extra moist meatloaf, use 80/20 ground beef. The fat content helps keep it tender.
  • If you do not have Stove Top Stuffing, substitute with 1 cup of plain dry breadcrumbs.
  • Resting the meatloaf before slicing is key to keeping the juices inside the loaf.

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